DTOX™ is designed to help alleviate the common side effects of alcohol consumption including irritability, sleep disturbances, and brain fog. Research suggests that the natural compounds in DTOX™ can support alcohol detoxification.+
The benefits include:
This natural formula combines Cysteine, NAC and Vitamin C with super antioxidants to quickly restore brain power and ease recovery in the morning.
Supports faster recovery in the morning†
Promotes Resilience to the Adverse Effects of Alcohol Consumption†
Enhances Efficient Disposal of Alcohol's Metabolic Byproduct†
Helps Reduce Brain Fog & Fatigue From Alcohol Consumption†
Take one capsule before each serving of alcohol, when exposed to environmental toxins, or as directed by a healthcare practitioner.
U.S.A. manufactured in a cGMP facility. Natural Stacks proudly uses only the highest quality ingredients.
What if you could have a drink (or a few!) without feeling the negative side effects?
DTOX™ is a alcohol detoxification formula designed for reducing hangover symptoms. It features powerful natural ingredients that block the conversion of alcohol to Acetaldehyde, the hangover-causing compound.
It also promotes the removal of toxins by replenishing lost nutrients. Super antioxidants scavenge harmful free radicals and protect the liver and immune system from alcohol-induced stress.
Alcohol --> Acetaldehyde --> Acetate
Your body uses key nutrients to break down Acetaldehyde, but since alcohol is a diuretic it quickly depletes the valuable vitamins and minerals necessary for the natural detoxification mechanisms. By super-charging your ability to break-down alcohol’s toxic metabolites DTOX™ enables you to avoid hangover symptoms, and it is essential to maintaining long-term brain health.
The combination Cysteine and Vitamin C creates a foundation for counteracting the toxic effect of alcohol and reducing stress on your body. Vitamin B-1 and R-Lipoic Acid help metabolize alcohol-induced toxins and replenish nutrients that may be depleted by alcohol. They are also mitochondrial co-factors that allow you to quickly restore brainpower, improve mitochondrial activity, and eliminate brain fog.
The ingestion of alcohol and its subsequent metabolism disrupts the body’s digestion, storage, utilization, and excretion of nutrients. 
Alcohol interferes with digestion by inhibiting the breakdown of nutrients into usable molecules by decreasing secretion of digestive enzymes from the pancreas. 
Alcohol further impairs nutrient absorption by causing damage to the cells lining the stomach and intestines and disables transport of some nutrients into the blood. 
Even if these crucial nutrients are digested and absorbed, alcohol can prevent them from being properly utilized by altering their transport, and storage.
Two critical nutrients depleted by alcohol are Thiamine (Vitamin B1) and Lipoic Acid.
Thiamine deficiency is actually one of the hallmarks of “Alcoholic Brain Disease”. 
Like most B vitamins, Thiamine (B1) plays a role in converting the food we eat into fuel. As noted above, alcohols depletion of these B vitamins impair our ability to assimilate nutrients we eat into food for fuel.
Thiamine also plays a role in critical several cognitive functions, including motor control, but also perceptual – motor tasks, executive functions, and learning and memory, all of which are impaired in alcoholics 
When consumes alcohol is broken down by the body in a multi-step process. One of the by products of the breakdown is aldehyde.
Aldehyde is the compound responsible that blocks normal molecular function, damages our liver, suppresses the immune system, causes accelerates wrinkling of the skin, and leads to the dreaded hangover. 
Blocking these toxic effects of aldehyde could reduce both the short and long-term negative impacts of alcohol.
Fortunately for us, the amino acid cysteine has been shown to prevent or block the toxic impact of aldehyde by binding to these molecules before they can interfere with normal biological functions. 
“A combination of l-ascorbic acid [Vitamin C] with l-cysteine, and thiamin·HCl [Vitamin B1] at reduced dose levels (2.0, 1.0 and 0.3 mM/kg, respectively) gave virtually complete protection.” 
Vitamin C is a well known antioxidant. 
It does not always have to exhibit its antioxidant properties on humans. It can direct those properties toward other molecules as it does when it prevents L-cysteine from being oxidized.  By keep L-cysteine in its unoxidized state, Cysteine is more available to block aldehyde’s toxic impact.
This same study also concluded that taking Vitamin C and Cysteine “along with ethanol (alcohol) attenuated the amount of oxidation which suggested that cysteine-methionine and vitamin C could play a protective role in the stomach against oxidative damage resulting from chronic alcohol ingestion.”
The combination of cysteine, Vitamin C, R-Lipoic Acid, and Vitamin B1 has been found to reduce feelings of alcohol-induced irritability, brain fog, sleep disruption, and generally increases functional capacity the day after alcohol consumption when consumed before each alcoholic beverage. 
A meta-analysis on heavy metal toxicity concluded that adjunctive therapies with the antioxidants N-acetyl-cysteine (NAC) and lipoic acid “have shown considerable promise in improving clinical recoveries in animal models.” [13,14,15]
Most companies use "proprietary blends" so they don't have to tell you the amount of each ingredient in their formulas. At Natural Stacks we believe it's your right to know exactly what you're putting into your body. We proudly publish our innovative formulas and ingredient suppliers in an open source format.
If for whatever reason you're unsatisfied with your Natural Stacks products, you can return the product within 30 days for a full refund. We also provide actionable tips on our blog and newsletter for you to maximize your performance with our premium products.
1. Gordis, E. M.D. Alcohol and Nutrition. National Institute of Alcohol Abuse and Alcoholism.
2. Korsten, M. A. (1989). Alcoholism and pancreatitis; does nutrition play a role?. Alcohol Health & Research World, 13(3), 232-238.
3. Feinman, L. (1989). Absorption and utilization of nutrients in alcoholism. Alcohol Health & Research World, 13(3), 206-211.
4. Thomson, A. D., & Pratt, O. E. (1992). Interaction of nutrients and alcohol: absorption, transport, utilization and metabolism. Nutrition and alcohol, 4, 75-99.
5. Martin, P. R., Singleton, C. K., & Hiller-Sturmhofel, S. (2003). The role of thiamine deficiency in alcoholic brain disease. Alcohol Research and Health, 27(2), 134-142.
6. Parks, M. H., Dawant, B. M., Riddle, W. R., Hartmann, S. L., Dietrich, M. S., Nickel, M. K., ... & Martin, P. R. (2002). Longitudinal brain metabolic characterization of chronic alcoholics with proton magnetic resonance spectroscopy. Alcoholism: Clinical and Experimental Research, 26(9), 1368-1380.
7. Koppaka, V., Thompson, D. C., Chen, Y., Ellermann, M., Nicolaou, K. C., Juvonen, R. O., ... & Vasiliou, V. (2012). Aldehyde dehydrogenase inhibitors: a comprehensive review of the pharmacology, mechanism of action, substrate specificity, and clinical application. Pharmacological reviews, 64(3), 520-539.
8. Peana, A. T., Assaretti, A. R., Muggironi, G., Enrico, P., & Diana, M. (2009). Reduction of Ethanol‐Derived Acetaldehyde Induced Motivational Properties by l‐Cysteine. Alcoholism: Clinical and Experimental Research, 33(1), 43-48.
9. Sprince, H., Parker, C. M., Smith, G. G., & Gonzales, L. J. (1974). Protection against acetaldehyde toxicity in the rat by L-cysteine, thiamin and L-2-methylthiazolidine-4-carboxylic acid. Inflammation Research, 4(2), 125-130.
10. Padayatty, S. J., Katz, A., Wang, Y., Eck, P., Kwon, O., Lee, J. H., ... & Levine, M. (2003). Vitamin C as an antioxidant: evaluation of its role in disease prevention. Journal of the American college of Nutrition, 22(1), 18-35.
11. Amanvermez, R., Tunçel, Ö. K., Demir, Ş., Kefeli, M., Bek, Y., & Çelik, C. (2008). Protective effects of cysteine, methionine and vitamin C on the stomach in chronically alcohol treated rats. Journal of Applied Toxicology, 28(5), 591-598.
12. Fowkes, S. Living With Alcohol. Cognitive Enhancement Research Institute. Smart Drug News [v5n5]. Copyright (c) 1996, 1997
13. Flora, S. J., & Pachauri, V. (2010). Chelation in metal intoxication. International journal of environmental research and public health, 7(7), 2745-2788.
14. Flora, S. J., Pande, M., Kannan, G. M., & Mehta, A. (2003). Lead induced oxidative stress and its recovery following co-administration of melatonin or N-acetylcysteine during chelation with succimer in male rats. Cellular and molecular biology (Noisy-le-Grand, France), 50, OL543-51.
15. Pande, M., & Flora, S. J. S. (2002). Lead induced oxidative damage and its response to combined administration of α-lipoic acid and succimers in rats. Toxicology, 177(2), 187-196.